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Afanat is used to treatment of non-small cell lung carcinoma (NSCLC).Itbecomes to the tyrosine kinase inhibitor family of the drug. It is takenby mouth. It is primarily used to treat cases of NSCLC that harbor variation inthe epidermal growth factor receptor (EGFR) chromosome. Afatinib is an effective and selective, irreversible ErbBfamily blocker. fatinib covalently binds to and irreversibly blocks indicatingfrom all homo and heterodimers formed by the ErbB family members EGFR (ErbB1),HER2 (ErbB2), ErbB3 and ErbB4. fatinib covalently binds to the kinase rule of EGFR (ErbB1), HER2 (ErbB2), andHER4 (ErbB4) and irreversibly inhibits tyrosine kinase autophosphorylation,resulting in the down-regulation of ErbB in.
Uses:
non-small cell lung carcinoma
Product details
Brand name: Afanat
International trade name: Gilotrif
Active substance: Afatinib
Strength: 20mg
Category: Anti Cancer
Manufacturer: Natco Pharma Ltd
Packaging: 28 Tablets
Product form: Tablet
Price: